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A Brief description of the EAGeR study |
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Available information shows that low-dose aspirin (LDA) may improve pregnancy outcomes. LDA appears to be safe and has few side effects. In this study, we will study the effects of LDA taken before pregnancy and continuing through week 36 of pregnancy. |
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Can I participate? |
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If you are between 18-40 years old, have had ONE or TWO pregnancy losses in the past, and want to become pregnant again, you may qualify for this very important study. Please contact us. |
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What will I need to do if I join the EAGeR study? |
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You will meet with a research nurse or staff once or twice a month. |
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We will ask you questions about your past and present medical and reproductive history. |
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We will take some simple measurements on you such as weight and height. |
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We will collect and test a small amount of your blood and urine at your visits. |
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You will take a daily folic acid pill along with a daily LDA pill or a placebo (a pill that contains NO medication). |
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You will collect and freeze a small amount of your urine each morning for two to three months. We will provide the supplies. |
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You will complete a short daily diary, which we will provide, for up to two months. |
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You be provided with a home fertility monitor to use throughout the study as well as home pregnancy tests. |
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What if I become pregnant? |
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You will continue to take your study pills. |
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We will provide you with an additional ultrasound early in your pregnancy. |
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We will keep in regular contact with you throughout your pregnancy. |
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You will collect and freeze a small amount of your urine each morning and complete a daily diary for one month. |
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We will get your permission to collect information about you and your baby from medical records. |
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You will continue to see your personal obstetrician as usual. |
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Are there risks? |
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There are small risks such as pain and bruising from the blood draw. |
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There are no known risks to you or your baby of LDA in the first 36 weeks of pregnancy. |
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If you have any side-effects, we will discuss the problem with you and act appropriately. |
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Potential Benefits |
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Close medical evaluations. |
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Use of a fertility monitor supplied by the study. |
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Will I be reimbursed? |
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You will be paid for your time and travel to study appointments. |
